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Molecular mechanism of staurosporine-induced apoptosis in osteoblasts
Smiles: [2H]C([2H])([2H])OC(=O)NC1NC2=CC(=CC=C2N=1)S(=O)CCC
InChi: InChI=1S/C33H30ClN5O3
InChiKey: SNHRLVCMMWUAJD-UHFFFAOYSA-N
NVS-CECR2-1 rlukast Molecular mechanism of staurosporine-induced apoptosisNVS CECR2 1, a non BET family Bromodomain (BRD) inhibitor, is a potent and selective cat eye syndrome chromosome region, candidate 2 (CECR2) inhibitor. NVS CECR2 1 binds to CECR2 BRD with high affinity (IC50=47 nM; KD=80 nM). NVS CECR2 1 exhibits cytotoxic activity and induces apoptosis against various cancer cells by targeting CECR2 as well as via CECR2 independent mechanism. Product information CAS Number: 1992047 61 6 Molecular Weight: 495. 68
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