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demonstrating no activity against class II HDACs
3 mg/kg IV and 1
126:246-258
InChi: InChI=1S/C20H17F6N5O2/c21-19(22
PLX5622 3 Bromide demonstrating no activity against classPLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0. 016 M; Ki=5. 9 nM). PLX5622 allows for extended and specific microglial elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals. Product information CAS Number: 1303420 67 8 Molecular Weight: 395. 41 Formula: C21H19F2N5O Chemical Name: 6 fluoro N [(5 fluoro 2 methoxypyridin 3 yl)methyl] 5 ({5 methyl
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