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Histopathology of DRESS has not been well specified and is labeled as EM-like, spongiotic, lichenoid, or toxic epidermal necrolysis like, which in turn reflects the variable clinical phenotype.[7] Whether a particular histopathological pattern or character predicts systemic involvement and thus disease severity is also debatable

Abbreviations CRP: C-reactive protein DHR: Drug hypersensitivity reactions DRESS: Drug reaction with eosinophilia and systemic symptoms INR: International normalized ratio LDH: Lactate dehydrogenase RegiSCAR: Register of Severe Cutaneous Adverse Reactions TARC: Serum thymus and activation-regulated chemokine References Demoly P, Adkinson NF, Brockow K, Castells M, Chiriac AM, Greenberger PA, Khan DA, Lang DM, Park HS, Pichler W, Sanchez-Borges M, Shiohara T, Thong BY

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