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36)/t17-/m1/s1
Formula: C56H94N14O20S
388(12):1271-82
IWR-1 inhibits cell proliferation and EMT even in the presence of TNF-α-induced cancer cell stimulation
Triclabendazole niliprole 36)/t17-/m1/s1Triclabendazole is an anthelmintic and fasciolicidal, binding to beta tubulin and preventing the polymerization of the microtubules of which they are part. Studies in vitro and or in infected animals suggest that triclabendazole and its active metabolites (sulfoxide and sulfone) are absorbed by the tegument of the immature and mature worms, leading to a decrease of the resting membrane potential, inhibition of tubulin function as well as protein and