ERK-IN-3 301 InChi: InChI=1S/C40H50O21/c1-4-16-17-8-9-53-35(50)20(17)13-54-37(16)60-40-33(31(47)29(45)25(12-42)59-40)56-22-7-5-6-18(27(22)43)36(51)57-23-10-19-21(34(49)52-3)14-55-38(26(19)15(23)2)61-39-32(48)30(46)28(44)24(11-41)58-39/h4-7

Name: ERK-IN-3 301 InChi: InChI=1S/C40H50O21/c1-4-16-17-8-9-53-35(50)20(17)13-54-37(16)60-40-33(31(47)29(45)25(12-42)59-40)56-22-7-5-6-18(27(22)43)36(51)57-23-10-19-21(34(49)52-3)14-55-38(26(19)15(23)2)61-39-32(48)30(46)28(44)24(11-41)58-39/h4-7
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InChi: InChI=1S/C40H50O21/c1-4-16-17-8-9-53-35(50)20(17)13-54-37(16)60-40-33(31(47)29(45)25(12-42)59-40)56-22-7-5-6-18(27(22)43)36(51)57-23-10-19-21(34(49)52-3)14-55-38(26(19)15(23)2)61-39-32(48)30(46)28(44)24(11-41)58-39/h4-7

CAS Number: 154130-99-1

In MCF-7 cells overexpressing GFP-α-tubulin

CAS Number: 2309-07-1

ERK-IN-3 301 InChi: InChI=1S/C40H50O21/c1-4-16-17-8-9-53-35(50)20(17)13-54-37(16)60-40-33(31(47)29(45)25(12-42)59-40)56-22-7-5-6-18(27(22)43)36(51)57-23-10-19-21(34(49)52-3)14-55-38(26(19)15(23)2)61-39-32(48)30(46)28(44)24(11-41)58-39/h4-7ERK IN 3 is a potent and orally active inhibitor of ERK. ERK IN 3 inhibits ERK1 2 with low single digit nM IC50 values. ERK IN 3 can be used for the research of cancers driven by RAS mutations. Product information CAS Number: 2055597 12 9 Molecular Weight: 473. 93 Formula: C22H25ClFN7O2 Chemical Name: N [(1S) 2 amino 1 (3 chloro 5 fluorophenyl)ethyl] 1 {5 methyl 2 [(oxan 4 yl)amino]pyrimidin 4 yl} 1H imidazole 4 carboxamide Smiles:

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