CL2A Abd-7 InChi: InChI=1S/C24H22F2N2O2/c25-19-4-1-3-17(13-19)22-5-2-12-28(22)15-16-6-9-20(10-7-16)30-23-11-8-18(24(27)29)14-21(23)26/h1

InChi: InChI=1S/C24H22F2N2O2/c25-19-4-1-3-17(13-19)22-5-2-12-28(22)15-16-6-9-20(10-7-16)30-23-11-8-18(24(27)29)14-21(23)26/h1

22(28)20(24(38)45-14)42-10(2)31)23(37)19(36)21(28)27(11

with a subnanomolar Kd toward PI3Kα and mTOR (0

24)/b19-11+

CL2A Abd-7 InChi: InChI=1S/C24H22F2N2O2/c25-19-4-1-3-17(13-19)22-5-2-12-28(22)15-16-6-9-20(10-7-16)30-23-11-8-18(24(27)29)14-21(23)26/h1CL2A is a claevable complicated PEG8 and triazole containing PABC peptide mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. Labetuzumab govitecan used this linker. Product information CAS Number: 2616704 22 2 Molecular Weight: 1062. 21 Formula: C50H79N9O16 Chemical Name: N [(1 {26 [2 ({[(1S) 5 amino 1 {[4