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it displayed potent antileukemic activity in bone marrow blasts from AML patients regardless of FLT3 mutation status
leading to the inhibition of the JAK/STAT (signal transducer and activator of transcription) signaling including activation of STAT3
59(12):7504-16
222638-67-7
Dihexa - CAS# 1401708-83-5. CAS# 1401708-83-5 043 it displayed potent antileukemic activityDihexa, CAS No. 1401708 83 5, also known as PNB 0408, N hexanoic Tyr Ile (6) aminohexanoic amide, CAS No. 1401708 83 5, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c Met. Dihexa has been found to potently improve cognitive function in animal models of Alzheimer's disease like mental impairment. In an assay of neurotrophic activity,