TCS 2002 iclopirox Chemical Name: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid

Chemical Name: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid

Chemical Name: 6-fluoro-3-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1

CAS Number: 25739-41-7

Chemical Name: 3-({4-hydroxy-1-[(3R

TCS 2002 iclopirox Chemical Name: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acidTCS 2002 is a potent inhibitor of GSK 3 with IC50 value of 35 nM . Glycogen synthase kinase 3 (GSK 3) is a serine threonine protein kinase and functions by phosphorylating a serine or threonine residue on its target protein. GSK3 plays an important role in neuronal cell development, energy metabolism and body pattern formation. TCS 2002 is a potent GSK 3 inhibitor with IC50 value of 35 nM. (S) TCS 2002 and (R) TCS 2002 inhibited GSK 3 with IC50 values