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regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38
including transcription factors crucial for the expression of genes needed to induce cell differentiation
also known as VTP-34072
GSK1904529A (72 h) inhibits tumor cells proliferation with IC50s ranges from 35 nM to >30 μM
Boc-C1-PEG3-C4-OBn sanib Diphosphate regulates intestinal epithelial cellular functionsBoc C1 PEG3 C4 OBn (PROTAC Linker 15) is a PROTAC linker, which refers to the PEG composition. Boc C1 PEG3 C4 OBn can be used in the synthesis of a series of PROTACs, such as PROTAC SGK3 degrader 1 (HY 125878). PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin proteasome system to selectively degrade target