7-Hydroxy-3, 4-dihydro-2(1H)-quinolinone fadine-A In agreement with NMR binding

In agreement with NMR binding and fluorescence polarization assays (FPAs) data

381(2):165-70

APD334 was efficacious in a mouse experimental autoimmune encephalomyelitis (EAE) model of MS and a rat collagen induced arthritis (CIA) model and was found to have appreciable central exposure

67 mg/mL (2

7-Hydroxy-3, 4-dihydro-2(1H)-quinolinone fadine-A In agreement with NMR binding7 Hydroxy 3,4 dihydro 2(1H) quinolinone (3,4 Dihydro 7 hydroxy 2(1H) quinolinone) is a weak MAO A inhibitor, with an IC50 of 183 M, and has no effect on MAO B. Product information CAS Number: 22246 18 0 Molecular Weight: 163. 17 Formula: C9H9NO2 Chemical Name: 7 hydroxy 1,2,3,4 tetrahydroquinolin 2 one Smiles: OC1C=CC2CCC(=O)NC=2C=1 InChiKey: LKLSFDWYIBUGNT UHFFFAOYSA N InChi: InChI=1S C9H9NO2 c11 7 3 1 6 2 4 9(12)10 8(6)5 7 h1,3,5,11H,2,4H2,(H,10,12)