MK-0674 macrenal HMC-1 cells incubated with A

HMC-1 cells incubated with A 943931 at a concentration of 300 nM for 20 min inhibited the increase in ALDH2 activity induced by H4R

61(5):953-63

compare to untreated control cells

Solubility: DMSO : 250 mg/mL (641

MK-0674 macrenal HMC-1 cells incubated with AMK 0674 is a potent, orally bioavailable and selective cathepsin K inhibitor, with an IC50 of 0. 4 nM, shows 1156, 1465, 11857 and 243 fold selectivity over Cat B, Cat F, Cat L and Cat S. Product information CAS Number: 887781 62 6 Molecular Weight: 527. 50 Formula: C26H27F6N3O2 Chemical Name: (2S) N (1 cyanocyclopropyl) 2 {[(1S) 1 {4' [(1R) 2,2 difluoro 1 hydroxyethyl] [1,1' biphenyl] 4 yl} 2,2,2 trifluoroethyl]amino} 4 fluoro 4 methylpentanamide