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is a potent 19S deubiquitinase inhibitors with great potential for anticancer drug development
pii: S1470-2045(14)71135-0
CAS Number: 1310455-86-7
5) and guinea pig (pK(i) = 7
CC-401 Catalog No.:M11289-2 is a potent 19S deubiquitinaseCC 401, also known as JNK 401, is a potent, selective, ATP competitive pan JNK inhibitor that decreases hepatic necrosis and apoptosis, significantly reduces tubular apoptosis in the obstructed kidney, sensitizes hypoxic colon cancer cells to DNA damaging agents, and potentiates the effect of bevacizumab and oxaliplatin in HT29 derived mouse xenografts. CC 401 Promotes Cell Replication via Pleiotropic Consequences of DYRK1A B Inhibition. Product
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