Aeroplysinin 1 NX-774 and increases the apoptosis rate

and increases the apoptosis rate at the high concentration (≥10 μM)

21-11-/t18-

male Balb/c nude mice) pretreatment decreases tumour growth in an in vivo mouse model

IC50: 10 μM for ET-1 binding to the ETA receptor ofA10 cells Asterric Acid is an ETA receptor inhibitor

Aeroplysinin 1 NX-774 and increases the apoptosis rateAeroplysinin 1 ((+) Aeroplysinin 1), a secondary metabolite isolated from marine sponges, shows potent antibiotic effects on Gram positive bacteria and exerts antiviral activity against HIV 1 (IC50=14. 6 M). Aeroplysinin 1 has anti inflammatory, anti angiogenic and anti tumor activities. Aeroplysinin 1 induces apoptosis in endothelial cells. Product information CAS Number: 28656 91 9 Molecular Weight: 338. 98 Formula: C9H9Br2NO3 Chemical Name: 2