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CAS Number: 321695-57-2
10(3-4):197-205
Trichophyton mentagrophytes
thereby blocking tumor angiogenesis
Vorinostat olnaftate CAS Number: 321695-57-2Vorinostat, also known as suberanilohydroxamic acid, MK 0683 and SAHA, is a potent and selective inhibitor of histone deacetylases (HDACs). Vorinostat has been shown to bind to the active site of histone deacetylases and act as a chelator for Zinc ions also found in the active site of histone deacetylases. Vorinostat's inhibition of histone deacetylases results in the accumulation of acetylated histones and acetylated proteins, including transcription