Etoposide yrphostin A1 our findings indicate that CID755673

our findings indicate that CID755673 is a potent and selective PKD1 inhibitor with valuable pharmacological and cell biological potential

IUBMB Life

Molecular Weight: 323

and suppresses experimental autoimmune encephalomyelitis

Etoposide yrphostin A1 our findings indicate that CID755673Etoposide is a semisynthetic derivative of podophyllotoxin and a substance extracted from the mandrake root Podophyllum peltatum. Possessing potent antineoplastic properties, etoposide binds to and inhibits topoisomerase II and its function in ligating cleaved DNA molecules, resulting in the accumulation of single or double strand DNA breaks, the inhibition of DNA replication and transcription, and apoptotic cell death. Etoposide acts primarily in the