MCL-1/BCL-2-IN-2 173v3 modulator 1 COC1=CC(=CC=C1NC1C=C(NC2=CC=CC=C2C(=O)NC)C(=CN=1)C(F)(F)F)N1CCOCC1

COC1=CC(=CC=C1NC1C=C(NC2=CC=CC=C2C(=O)NC)C(=CN=1)C(F)(F)F)N1CCOCC1

buckthorn and Japanese knotweed (Fallopia japonica syn

Molecular Weight: 1088

β or γ with IC50>1 mM

MCL-1/BCL-2-IN-2 173v3 modulator 1 COC1=CC(=CC=C1NC1C=C(NC2=CC=CC=C2C(=O)NC)C(=CN=1)C(F)(F)F)N1CCOCC1MCL 1 BCL 2 IN 2 (Compound 6) is a potent and selective Mcl 1 and Bcl 2 dual inhibitor. Product information CAS Number: 2163793 44 8 Molecular Weight: 427. 31 Formula: C20H15BrN2O2S Chemical Name: 3 (2 aminoethyl) 8 [(4 bromophenyl)sulfanyl] 3 azatricyclo[7. 3. 1. 0,]trideca 1(13),5,7,9,11 pentaene 2,4 dione Smiles: NCCN1C(=O)C2C=CC=C3C=2C(=CC=C3SC2C=CC(Br)=CC=2)C1=O InChiKey: LPOALFWTLPKKNW UHFFFAOYSA N InChi: InChI=1S C20H15BrN2O2S c21 12 4 6 13(7 5