JI-101 S-9876) Smiles: CC(C)(CCC(=O)N(C)[C@@H](C)C(=O)O[C@H]1CC(=O)N(C)C2C=C(CC(C)=CC=C[C@@H](OC)[C@@]3(O)CC(OC(=O)N3)[C@@H](C)[C@@H]3O[C@@]13C)C=C(OC)C=2Cl)SSCCC(=O)ON1C(=O)CCC1=O |t:25

Smiles: CC(C)(CCC(=O)N(C)[C@@H](C)C(=O)O[C@H]1CC(=O)N(C)C2C=C(CC(C)=CC=C[C@@H](OC)[C@@]3(O)CC(OC(=O)N3)[C@@H](C)[C@@H]3O[C@@]13C)C=C(OC)C=2Cl)SSCCC(=O)ON1C(=O)CCC1=O |t:25

2 and 5 μM Neferine are used in the remaining experiments

InChiKey: LEVWYRKDKASIDU-IMJSIDKUSA-N

Glut1 deficiency syndrome and erythrocyte glucose uptake assay

JI-101 S-9876) Smiles: CC(C)(CCC(=O)N(C)[C@@H](C)C(=O)O[C@H]1CC(=O)N(C)C2C=C(CC(C)=CC=C[C@@H](OC)[C@@]3(O)CC(OC(=O)N3)[C@@H](C)[C@@H]3O[C@@]13C)C=C(OC)C=2Cl)SSCCC(=O)ON1C(=O)CCC1=O |t:25JI 101 is an orally available multi kinase inhibitor of VEGFR2, PDGFR and EphB4 with potent anti cancer activity. Product information CAS Number: 900573 88 8 Molecular Weight: 466. 33 Formula: C22H20BrN5O2 Chemical Name: 3 {1 [(2 aminopyridin 4 yl)methyl] 1H indol 4 yl} 1 (5 bromo 2 methoxyphenyl)urea Smiles: COC1=CC=C(Br)C=C1NC(=O)NC1=CC=CC2=C1C=CN2CC1=CC(N)=NC=C1 InChiKey: ZXBFYBLSJMEBEP UHFFFAOYSA N InChi: InChI=1S C22H20BrN5O2 c1 30 20 6 5