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CAS Number: 1687736-54-4
exhibits a submicromolar IC50 in 10 of 10 multiple myeloma cell lines (MM1
Vet Microbiol
(2010) Proc Natl Acad Sci USA
BRD PHOTAC-I-3 Catalog No.:M7566-10 CAS Number: 1687736-54-4BRD PHOTAC I 3 is a photoswitchable BET bromodomain degrader (PHOTAC, PHOtochemically TArgeting Chimera). BRD PHOTAC I 3 comprises a ligand for an E3 ligase, a photoswitch, and the BET bromodomain targeting ligand (+) JQ1 (Cat. No. 4499). Exhibits cytotoxicity and degrades BRD4, BRD3 and to a lesser extent BRD2 in lymphoblast cells upon irradiation with 390 nm light, but not in the dark. Product information CAS Number: 2370997 94 5 Molecular Weight:
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