Medicarpin - CAS# 32383-76-9 Catalog No.:M12563-10 Smiles: CSSC(C)(C)CCC(=O)NC1C=C2C=C(NC2=CC=1)C(=O)NC1C=C2C=C(NC2=CC=1)C(=O)N1C[C@@H](CCl)C2C3=CC=CC=C3C(O)=CC1=2

Smiles: CSSC(C)(C)CCC(=O)NC1C=C2C=C(NC2=CC=1)C(=O)NC1C=C2C=C(NC2=CC=1)C(=O)N1C[C@@H](CCl)C2C3=CC=CC=C3C(O)=CC1=2

4 mg/kg MK-8776 S-isomer is sufficient to induce the γ-H2AX biomarker while 8 mg/kg leads to enhanced tumor pharmacodynamic and regression responses relative to gemcitabine or MK-8776 S-isomer alone

PubMed PMID: 24900311

[Epub ahead of print] PubMed PMID: 25627448

Medicarpin - CAS# 32383-76-9 Catalog No.:M12563-10 Smiles: CSSC(C)(C)CCC(=O)NC1C=C2C=C(NC2=CC=1)C(=O)NC1C=C2C=C(NC2=CC=1)C(=O)N1C[C@@H](CCl)C2C3=CC=CC=C3C(O)=CC1=2Medicarpin is a flavonoid isolated from Medicago sativa. Medicarpin induces apoptosis and overcome multidrug resistance in leukemia P388 cells by modulating P gp mediated efflux of drugs. Product information CAS Number: 32383 76 9 Molecular Weight: 270. 28 Formula: C16H14O4 Chemical Name: (1R, 10R) 14 methoxy 8, 17 dioxatetracyclo[8. 7. 0. 0, . 0, ]heptadeca 2, 4, 6, 11, 13, 15 hexaen 5 ol Smiles: COC1=CC2O[C@@H]3[C@@H](COC4=CC(O)=CC=C43)C=2C=C1