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Selumetinib sulfate 1123 11aH-cyclopenta[a]phenanthren-1-yl]-2-methyl-5-(propan-2-yl)-2

SKU: 21901806524

4.5
USD100.00 USD132.00

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Description

11aH-cyclopenta[a]phenanthren-1-yl]-2-methyl-5-(propan-2-yl)-2

NCCNC(=O)O[C@@H]1C[C@H]2C(=O)N[C@@H](C3C=CC=CC=3)C(=O)N[C@H](CC3=CNC4=CC=CC=C34)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC3C=CC(=CC=3)OCC3C=CC=CC=3)C(=O)N[C@@H](CC3C=CC=CC=3)C(=O)N2C1

which occurrs at 0

24(5):1884-1892

Selumetinib sulfate 1123 11aH-cyclopenta[a]phenanthren-1-yl]-2-methyl-5-(propan-2-yl)-2Selumetinib (AZD6244) is selective, non ATP competitive oral MEK1 2 inhibitor, with an IC50 of 14 nM for MEK1. Selumetinib (AZD6244) inhibits ERK1 2 phosphorylation. Product information CAS Number: 943332 08 9 Molecular Weight: 555. 76 Formula: C17H17BrClFN4O7S Chemical Name: 5 [(4 bromo 2 chlorophenyl)amino] 4 fluoro N (2 hydroxyethoxy) 1 methyl 1H 1,3 benzodiazole 6 carboxamide; sulfuric acid Smiles:

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