FTI-277 Hydrochloride Size:Solid 10 mg InChiKey: KSERXGMCDHOLSS-LJQANCHMSA-N

InChiKey: KSERXGMCDHOLSS-LJQANCHMSA-N

with a maximal inhibition of ~90% at 500 µM (n≥5 cells at each concentration)

Formula: C7H9NO6S

while the rest of the strains are inhibited by Enrofloxacin with MICs ≤0

FTI-277 Hydrochloride Size:Solid 10 mg InChiKey: KSERXGMCDHOLSS-LJQANCHMSA-NFTI 277 is a peptide mimetic of the COOH terminal Cys Val Ile Met of K Ras4B that inhibited potently FTase in vitro (IC50 = 500 pM) and was highly selective for FTase over geranylgeranyltransferase I (GGTase I) (IC50 = 50 nM). FTI 277, the methyl ester derivative of FTI 276, was extremely potent (IC50 = 100 nM) at inhibiting H Ras, but not the geranylgeranylated Rap1A processing in whole cells. Product information CAS Number: 180977 34 8 Molecular