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toremifene citrate is FDA-approved for use in advanced (metastatic) breast cancer
Tandutinib inhibits cell proliferation of the FLT3-ITD-positive Molm-13 and Molm-14 with an IC50 of 10 nM
important in long-term potentiation
Burghardt TP
GRL-0496 - CAS# 1087243-14-8 D9567 toremifene citrate is FDA-approved forGRL 0496 is a potent chloropyridyl ester derived SARS CoV 3CLpro inhibitor, with an IC50 of 30 nM in both enzyme inhibitory and antiviral assays. GRL 0496 shows SARS CoV antiviral activity, with an EC50 of 6. 9 M. Product information CAS Number: 1087243 14 8 Molecular Weight: 272. 69 Formula: C14H9ClN2O2 Chemical Name: 5 chloropyridin 3 yl 1H indole 4 carboxylate Smiles: O=C(OC1=CN=CC(Cl)=C1)C1C=CC=C2NC=CC=12 InChiKey: BOSZJNSICHFHMA UHFFFAOYSA N
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