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(S, S, S)-AHPC hydrochloride Catalog No.:M24466-C AZ32 blocks the DNA damage

SKU: 22984046172

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Description

AZ32 blocks the DNA damage response and radiosensitized GBM cells in vitro

Chemical Name: {4-[(2S)-3-carbamoyl-2-[(2S)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]propanamido]propanamido]phenyl}methyl 4-nitrophenyl carbonate

Smiles: C[C@@H](CC)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(O)=O)[C@@H](C)CC)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(N)=O

and induced with TNF-α for 20 h

(S, S, S)-AHPC hydrochloride Catalog No.:M24466-C AZ32 blocks the DNA damage(S,S,S) AHPC hydrochloride is a von Hippel Lindau (VHL) amino building block. (S,S,S) AHPC (Compound 27) is a ligand used as a negative control for (S,R,S) AHPC. (S,R,S) AHPC is the VH032 based VHL ligand used in the recruitment of the VHL protein. Product information CAS Number: 2115897 23 7 Molecular Weight: 467. 02 Formula: C22H31ClN4O3S Chemical Name: (2S,4S) 1 [(2S) 2 amino 3,3 dimethylbutanoyl] 4 hydroxy N {[4 (4 methyl 1,3 thiazol 5

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