8-CPT-2Me-cAMP, sodium salt 283psilon-(gamma-glutamyl)-lysine CCCCCCCCCC(=O)CC(O)S([O-])(=O)=O

CCCCCCCCCC(=O)CC(O)S([O-])(=O)=O

CAS Number: 2313525-20-9

In human tumor cell lines

Palyzová A

8-CPT-2Me-cAMP, sodium salt 283psilon-(gamma-glutamyl)-lysine CCCCCCCCCC(=O)CC(O)S([O-])(=O)=O8 CPT 2Me cAMP, sodium salt is a selective agonist of EPAC . Cyclic AMP guanine nucleotide exchange factors (EPACs) are intracellular sensors for cAMP and function as nucleotide exchange factors for the Ras GTPase homologues Rap1 and Rap2 . 8 CPT 2Me cAMP, sodium salt is a selective EPAC agonist. 8 CPT 2Me cAMP increased Rap1 activation by EPAC1. Meantime, light chain 2 (LC2) of the microtubule associated protein MAP1A increased this response. In LC2