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63(13):3637-45
also known as Mal-heptanoic NHS ester
Incubation of cells with UCN-01 or Go-6976 alone do not decrease viability compared with control at the concentrations used
This agent also inhibits other tyrosine kinases including those associated with vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs)
Bay 11-7085 - CAS# 196309-76-9 Catalog No.:M6654-10 63(13):3637-45Bay 11 7085, CAS No. 196309 76 9, a soluble inhibitor of NK kappaB activation, has been shown to inhibit cell proliferation and induce apoptosis of a variety of cells. Bay 11 7085 induces apoptosis of ECSCs by suppressing antiapoptotic proteins, and that caspase 3 , 8 , and 9 mediated cascades are involved in this mechanism. Bay 11 7085 could be used as a therapeutic agent for the treatment of endometriosis. Bay 11 7085 protects against gut ischemia
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