![GNF-5837 200vermectin Smiles: O=C(NC1=NC=C(S1)SCCN1CCCC1)[C@@]1(C[C@H]1C1CCCCC1)C1C=CC(=CC=1)S(=O)(=O)C1CC1](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M9916_1621561015.gif?v=1621561016)
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Smiles: O=C(NC1=NC=C(S1)SCCN1CCCC1)[C@@]1(C[C@H]1C1CCCCC1)C1C=CC(=CC=1)S(=O)(=O)C1CC1
is a noncompetitive antagonist of the NMDA receptor
GNE-6776 interacts with acidic residues that mediate hydrogen-bond interactions with the ubiquitin Lys48 side chain
Erismodegib selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo
GNF-5837 200vermectin Smiles: O=C(NC1=NC=C(S1)SCCN1CCCC1)[C@@]1(C[C@H]1C1CCCCC1)C1C=CC(=CC=1)S(=O)(=O)C1CC1GNF 5837 is a potent, selective, and orally bioavailable pan TRK inhibitor that inhibited tumor growth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. The properties of GNF 5837 make it a good tool for the elucidation of TRK biology in cancer and other nononcology indications. Product information CAS Number: 1033769 28 6 Molecular Weight: 535. 49 Formula: C28H21F4N5O2 Chemical Name: 1 [2 fluoro 5
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