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It covalently binds to the cysteine 88 of ubiquitin receptor RPN13 in the 19S regulatory particle and inhibits proteasome function
InChi: InChI=1S/C23H30N8O3S/c1-14-17(13-29-3-5-31(6-4-29)22(33)15(2)32)35-19-18(14)27-20(16-11-25-23(24)26-12-16)28-21(19)30-7-9-34-10-8-30/h11-12
CTNNB1 and GSK3B as compare to osteogenic medium alone on day 7
TAK-779 did not affect production of IL-12 by antigen-presenting cells
Curcumol - CAS# 4871-97-0 acaftor (benzenesulfonate) It covalently binds to theCurcumol (( ) Curcumol), a bioactive sesquiterpenoid, possesses numerous pharmacological activities like anticancer, antimicrobial, antifungal, antiviral, and antiinflammatory. Curcumol is a potent inducer of apoptosis in numerous cancer cells via targeting key signaling pathways as MAPK ERK, PI3K Akt and NF B which are generally deregulated in several cancers. Product information CAS Number: 4871 97 0 Molecular Weight: 236. 35 Formula: C15H24O2