SNX-5422 Mesylate (PF-04929113 (Mesylate)) Size:Contact [email protected] for quotation while produces no significant suppression

while produces no significant suppression when used alone

12-heptaene-8

InChi: InChI=1S/C18H19ClN4O

Idalopirdine

SNX-5422 Mesylate (PF-04929113 (Mesylate)) Size:Contact [email protected] for quotation while produces no significant suppressionSNX 5422 Mesylate (PF 04929113 Mesylate), a prodrug of SNX 2112, is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her 2 degradation, with an IC50 of 37 nM. SNX 5422 is an orally active Hsp90 inhibitor, with a Kd of 41 nM, and also induces Her 2 degradation, with an IC50 of 37 nM. SNX 5422 exhibits potent effects on Her2 and p ERK stability in AU565 cells and p S6 in A375 cells, with IC50s of 5 1, 11 3, and 61 22 nM,