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Formula: C13H22Br2Cl2N2
Distrutti E
and the inhibition is reversible
Conduritol B epoxide-N2a cells show a significant reduction in OCR as evidenced by approximately 50% in all the parameters
4SC-202 free base xiben HCl Formula: C13H22Br2Cl2N2Domatinostat, also known as 4SC 202, is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC 202 selectively binds to and inhibits class I HDACs leading to an accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, the selective transcription of tumor suppressor genes, and the tumor