C-021 dihydrochloride dium formononetin-3'-sulfonate HIF-C2 is selective for the

HIF-C2 is selective for the HIF-2 isoform and has no activity to antagonize HIF-1

respectively) and is inactive against a general panel of over 200 kinases when tested at 10 µM

InChiKey: QIFJOFNVIVQRNJ-UHFFFAOYSA-N

Chemical Name: 4-{2-[(2-{4-[(2E)-4-{3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3

C-021 dihydrochloride dium formononetin-3'-sulfonate HIF-C2 is selective for theC 021 dihydrochloride is a potent CC chemokine receptor 4 (CCR4) antagonist. C 021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C 021 effectively prevents human CCL22 derived [35S]GTPS from binding to the receptor with an IC50 of 18 nM. Product information CAS Number: 1784252 84 1 Molecular Weight: 540. 57 Formula: C27H43Cl2N5O2 Chemical Name: (4E) 2 {[1,4' bipiperidin] 1' yl}