A-366 044SB069 Smiles: [2H]C(NCC(O)C1=CC=CC=C1Cl)(C([2H])([2H])[2H])C([2H])([2H])[2H]

Smiles: [2H]C(NCC(O)C1=CC=CC=C1Cl)(C([2H])([2H])[2H])C([2H])([2H])[2H]

is a potent protein kinase CK2 inhibitor

Smiles: NCCOCCOCCOCCC(=O)NC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

exhibits high binding affinity to melanocortin 1 receptor (MC1R) with a Ki of 0

A-366 044SB069 Smiles: [2H]C(NCC(O)C1=CC=CC=C1Cl)(C([2H])([2H])[2H])C([2H])([2H])[2H]A 366 is a potent, highly selective, peptide competitive histone methyltransferase G9a inhibitor with IC50s of 3. 3 and 38 nM for G9a and GLP (EHMT1), respectively. A 366 shows >1000 fold selectivity over 21 other methyltransferases. A 366 is also a potent, nanomolar inhibitor of the Spindlin1 H3K4me3 interaction (IC50=182. 6 nM). A 366 displays high affinity at human histamine H3 receptor (Ki=17 nM) and shows subtype selectivity among subsets of the