IPI-3063 axyl-M InChi: InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14

InChi: InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14

GSK040 shows more than 5000-fold selectivity for BET BD2 over BET BD1 (pIC50=4

InChi: InChI=1S/C16H15ClN5O5PS2/c17-7-1-3-8(4-2-7)30-16-21-10-13(18)19-6-20-14(10)22(16)15-11(23)12-9(26-15)5-25-28(24

75 mg/kg)+oxycodone+oxycodone group

IPI-3063 axyl-M InChi: InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14IPI 3063 is a potent and selective PI3K p110 inhibitor with an IC50 of 2. 5 1. 2 nM. Product information CAS Number: 1425043 73 7 Molecular Weight: 455. 51 Formula: C25H25N7O2 Chemical Name: 4 amino 6 {[(1S) 1 [8 (1 methyl 6 oxo 1,6 dihydropyridin 3 yl) 1 oxo 2 (propan 2 yl) 1,2 dihydroisoquinolin 3 yl]ethyl]amino}pyrimidine 5 carbonitrile Smiles: CN1C=C(C=CC1=O)C1=CC=CC2C=C([C@H](C)NC3N=CN=C(N)C=3C#N)N(C(C)C)C(=O)C=21 InChiKey: OBHAYOJCPNWKBL