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22(12):3001-11
MKC-3946 is an IRE1α endoribonuclease domain inhibitor that blocks XBP1 mRNA splicing and triggers modest growth inhibition in MM cells
In HSV-infected cells
p53 and MDM2 proteins-interaction-inhibitor racemic is an inhibitor of the interaction between p53 and MDM2 proteins
Isavuconazole ndinavir sulfate 22(12):3001-11Isavuconazole, also knownc as BAL4815 and RO 0094815, is a triazole antifungal drug. Its prodrug, isavuconazonium sulfate (BAL8557), was granted approval by the U. S. Food and Drug Administration (FDA) on March 6, 2015 for the treatment of invasive candidiasis. Isavuconazole works by inhibiting lanosterol 14 alpha demethylase, the enzyme responsible for converting lanosterol to ergosterol by demethylation. The resulting depletion of ergosterol and