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) as a single agent (top panel) or in combination with radiation (bottom panel) results in an increase in fluorescence intensity in the Calu-6 tumors
Chemical Name: (4E)-4-[(2
Novobiocin: redesigning a DNA gyrase inhibitor for selective inhibition of hsp90
a potent ROCK inhibitor
Bendamustine Hydrochloride ntan Hydrochloride ) as a single agentBendamustine is a bifunctional mechlorethamine derivative with alkylator and antimetabolite activities. Bendamustine possesses three active moieties: an alkylating group; a benzimidazole ring, which may act as a purine analogue; and a butyric acid side chain. Although its exact mechanism of action is unknown, this agent appears to act primarily as an alkylator. Bendamustine metabolites alkylate and crosslink macromolecules, resulting in DNA, RNA and
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