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Folinic acid (calcium salt pentahydrate) relin InChi: InChI=1S/C18H18F3N3O/c19-18(20

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Description

InChi: InChI=1S/C18H18F3N3O/c19-18(20

Epub 2019 Jan 22

Discovery of CP-690

InChiKey: WOSKHXYHFSIKNG-UHFFFAOYSA-N

Folinic acid (calcium salt pentahydrate) relin InChi: InChI=1S/C18H18F3N3O/c19-18(20Leucovorin calcium is a n active metabolite of folic acid (also called folinic acid and citrovorum factor), which does not require metabolism by dihydrofolate reductase, the molecular target of folate antagonist type chemotherapeutic drugs. Leucovorin calcium counteracts the toxic effects of these medications, 'rescuing' the patient while permitting the antitumor activity of the folate antagonist. This agent also potentiates the effects of

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