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BMS-819881 also is selective and potent for CYP3A4 activity with an EC50 of 13 μM
CAS Number: 65141-46-0
Indeglitazar shows an EC50 of 0
ultrasonic and adjust pH to 11 with H2O) H2O : 0
BI-882370 evodopa BMS-819881 also is selective andBI 882370 is a potent and selective RAF kinase inhibitor that binds to the ATP binding site of the kinase positioned in the DFG out (inactive) conformation of the BRAF kinase. BI 882370 (BI 882370) inhibits the oncogenic BRAFV600E mutant, the WT BRAF and CRAF kinases with IC50s of 0. 4, 0. 8, and 0. 6 nM, respectively. BI 882370 also inhibits SRC family kinases. Product information CAS Number: 1392429 79 6 Molecular Weight: 569. 67 Formula:
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