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R Ten Broeke
is one of the most potent and selective small-molecule agonists of the Hedgehog pathway
4-dihydroxyphenyl)acetamide
As of 2011
RO-5963 - CAS# 1416663-77-8 azono)butane-1 3-dione R Ten BroekeRO 5963 is a dual p53 MDM2 and p53 MDMX inhibitor with IC50s of ~17 nM and ~24 nM, respectively. Product information CAS Number: 1416663 77 8 Molecular Weight: 518. 90 Formula: C24H21ClF2N4O5 Chemical Name: 2 [(4E) 4 [(6 chloro 7 methyl 1H indol 3 yl)methylidene] 2, 5 dioxoimidazolidin 1 yl] 2 (3, 4 difluorophenyl) N (1, 3 dihydroxypropan 2 yl)acetamide Smiles: CC1=C(Cl)C=CC2=C1NC=C2 C=C1 NC(=O)N(C(C2=CC(F)=C(F)C=C2)C(=O)NC(CO)CO)C 1=O InChiKey:
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