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Thalidomide-PEG2-C2-NH2 Catalog No.:M13080-2 Ibrutinib significantly reduces clinical arthritis

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Description

Ibrutinib significantly reduces clinical arthritis scores reflecting paw swelling and joint inflammation by inhibiting B-cell activation

Smiles: OC(C1CO1)C(O)C1CO1

InChi: InChI=1S/C19H18N2O2/c1-13(22)17-11-16(19-20-9-4-10-21(17)19)15-5-2-3-6-18(15)23-12-14-7-8-14/h2-6

SHP2 Inhibition Prevents Adaptive Resistance to MEK Inhibitors in Multiple Cancer Models

Thalidomide-PEG2-C2-NH2 Catalog No.:M13080-2 Ibrutinib significantly reduces clinical arthritisThalidomide PEG2 C2 NH2 is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and 2 unit PEG linker used in PROTAC technology. Product information CAS Number: 2093416 32 9 Molecular Weight: 404. 42 Formula: C19H24N4O6 Chemical Name: 4 ({2 [2 (2 aminoethoxy)ethoxy]ethyl}amino) 2 (2,6 dioxopiperidin 3 yl) 2,3 dihydro 1H isoindole 1,3 dione Smiles: NCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

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