CAL-101 - CAS# 870281-82-6 richlormethiazide Formula: C25H20F3N5O2

Formula: C25H20F3N5O2

and 6 out of 6 rats in Gr

TEPP-46 was dosed to mice orally at 50 mg/Kg twice per day

also known as BMS-512148

CAL-101 - CAS# 870281-82-6 richlormethiazide Formula: C25H20F3N5O2Idelalisib, also known as CAL 101, is a PI3K delta inhibitor with potential immunomodulating and antineoplastic activities. CAL 101 inhibits the production of the second messenger phosphatidylinositol 3,4,5 trisphosphate (PIP3), preventing the activation of the PI3K signaling pathway and thus inhibiting tumor cell proliferation, motility, and survival. Unlike other isoforms of PI3K, PI3K delta is expressed primarily in hematopoietic lineages. The