PF-5274857 hydrochloride Catalog No.:M17252-C CEM114 is an effective chemical

CEM114 is an effective chemical epigenetic modifier (CEM) that recruits endogenous chromatin machinery through CRISPR-Cas9 systems

5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-3

Sirtori CR

1-8H3/t17-

PF-5274857 hydrochloride Catalog No.:M17252-C CEM114 is an effective chemicalPF 5274857 hydrochloride is a potent, selective, orally active and brain penetrant antagonist of Smo, with an IC50 of 5. 8 nM and Ki of 4. 6 nM. PF 5274857 hydrochloride has potential for research of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway. Product information CAS Number: 1613439 62 5 Molecular Weight: 473. 42 Formula: C20H26Cl2N4O3S Chemical Name: 1 (4 {5' chloro 3,5 dimethyl [2,4' bipyridin] 2'