Sp-5, 6-dichloro-cBIMPS (sodium salt) Catalog No.:M22522-C CAS Number: 361154-30-5

CAS Number: 361154-30-5

CFI-402257 is found to be similarly efficacious in a platinum-sensitive PDX model of high-grade serous ovarian cancer

InChiKey: CMYCCJYVZIMDFU-UHFFFAOYSA-N

Probe Reports from the NIH Molecular Libraries Program[Internet]

Sp-5, 6-dichloro-cBIMPS (sodium salt) Catalog No.:M22522-C CAS Number: 361154-30-5Ki: 30 nM Sp 5,6 dichloro cBIMPS is a PKA activator. In cell biology, protein kinase A (PKA) is a family of enzymes whose activity is dependent on cellular levels of cyclic AMP. PKA is also known as cAMP dependent protein kinase. PKA has several functions in the cell, such as regulation of sugar, glycogen, and lipid metabolism. In vitro: Sp 5,6 dichloro cBIMPS was found to be both a potent and specific activator of purified cAMP PK and of cAMP PK in