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Chemical Name: 2-[3-(2-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-5-methyl-7H-pyrrolo[2
InChiKey: RKEWSXXUOLRFBX-UHFFFAOYSA-N
InChiKey: AVKUERGKIZMTKX-IEEUEUFMSA-N
Smiles: NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CC1C=CC(O)=CC=1
SPR inhibitor 3 J4 hydrochloride Chemical Name: 2-[3-(2-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-5-methyl-7H-pyrrolo[2SPR inhibitor 3 (SPRi3) is a potent sepiapterin reductase (SPR) inhibitor. SPR inhibitor 3 (SPRi3) displays high binding affinity to human SPR in a cell free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell based assay (IC50=5. 2 M). SPR inhibitor 3 (SPRi3) reduces neuropathic and inflammatory pain through a reduction of BH4 levels. Product information CAS Number: 1292285 54 1 Molecular Weight: 262. 30 Formula: C14H18N2O3 Chemical