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and caspase-9 and poly (ADP) ribosome polymerase
24(3):837-46
It was identified by an imaging-based high throughput screening in human MSCs
orally bioavailable
Verteporfin (Visudyne) - YAP Inhibitor. CAS# 129497-78-5 045 and caspase-9 and poly (ADP)Verteporfin (Visudyne), CAS No. 129497 78 5, is a potent and selective YAP inhibitor, disrupts YAP TEAD interactions and enhances trypsin cleavage of YAP with EC50 ~100 nM. It inhibits growth and proliferation of retinoblastoma cells. It also significantly blocks cancer stem cell (CSC) properties in cells with high YAP1 and a high proportion of ALDH1(+). In vivo it can suppress YAP induced liver overgrowth in mice. Product information CAS Number:
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