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S-(2-aminoethyl) Isothiourea (dihydrobromide) 684PADS tetrasodium and myocardial fibrosis and attenuates

SKU: 36899894585

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Description

and myocardial fibrosis and attenuates hypertrophic and profibrotic gene expression in mice harboring heterozygous human mutations in the myosin heavy chain

Formula: C34H28N4O5

Chemical Name: 2-{[(3-methyl-1

InChiKey: WUEHURHTEPWPPO-QZTJIDSGSA-N

S-(2-aminoethyl) Isothiourea (dihydrobromide) 684PADS tetrasodium and myocardial fibrosis and attenuatesS (2 aminoethyl) Isothiourea (dihydrobromide) is a potent and non selective inhibitor of NOS with Ki values of 1. 8, 2. 1, and 0. 59 M for human nNOS, eNOS, and iNOS, respectively . In the brain, nitric oxide (NO), which is synthesized from L arginine (Arg) by NO synthase (NOS), acts as both an intra and an intercellular second messenger. Nitric oxide synthase (iNOS, eNOS, and nNOS) catalyzed the production of NO in the two step oxidation of L

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