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PF-562271 besylate - CAS# 939791-38-5 aminophen metabolite 3-hydroxy-acetaminophen ML364 has an IC50 of

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Description

ML364 has an IC50 of 1

CAS Number: 136-47-0

The combination had greater efficacy than either reparixin or docetaxel alone

CAS Number: 127294-70-6

PF-562271 besylate - CAS# 939791-38-5 aminophen metabolite 3-hydroxy-acetaminophen ML364 has an IC50 ofPF 562271 Besylate, also known as PF 562,271 and PF 271, is an orally bioavailable small molecule and ATP competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF 562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival. Note: PF 562271 benzesulfonate is also called PF 562271

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