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Dacomitinib itein Smiles: CN1CCN(CC1)C1CCC(CC1)N1C=C(C2=C(N)N=CN=C12)C1C=CC(=CC=1)OC1C=CC=CC=1

SKU: 38259842294

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Description

Smiles: CN1CCN(CC1)C1CCC(CC1)N1C=C(C2=C(N)N=CN=C12)C1C=CC(=CC=1)OC1C=CC=CC=1

109(41):16708-13

Desloratadine is a tricyclic H1-antihistamine that is used to treat allergies

InChiKey: RXSARIJMSJWJLZ-CIAYNJNFSA-N

Dacomitinib itein Smiles: CN1CCN(CC1)C1CCC(CC1)N1C=C(C2=C(N)N=CN=C12)C1C=CC(=CC=1)OC1C=CC=CC=1Dacomitinib, also known as PF 299 and PF 00299804 ; or PF299804, is an orally bioavailable, highly selective, second generation small molecule inhibitor of the pan epidermal growth factor receptor (EGFR) family of tyrosine kinases (ErbB family) with potential antineoplastic activity. Dacomitinib specifically and irreversibly binds to and inhibits human EGFR subtypes, resulting in inhibition of proliferation and induction of apoptosis in EGFR

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