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"rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor
R59022 blocks entry of EBOV pseudotypes in a concentration-dependent manner (IC50: ~5 µM)
InChi: InChI=1S/C21H19FN6O2/c1-11-15-7-13(22)4-5-14(15)21(29)27(2)10-16-19(17(8-23)28(3)26-16)12-6-18(30-11)20(24)25-9-12/h4-7
The first class (DuP-753 sensitive) represents approximately 85% of the total binding sites for AII and possesses a high affinity (IC50 of 92
Silvestrol (aglycone) Catalog No.:M8405-2 "rule of 5" compliant andSilvestrol aglycone is a Silvestrol analogue, inhibits protein translation initiation in cancer cells, with EC50s of 10 and 200 nM for myc LUC and tub LUC luciferase reporter protein translation, respectively. Anti cancer activity. Product information CAS Number: 960365 65 5 Molecular Weight: 478. 49 Formula: C27H26O8 Chemical Name: methyl (2S,3R,4R,5S,6R) 2,3,10 trihydroxy 12 methoxy 6 (4 methoxyphenyl) 5 phenyl 7 oxatricyclo[6. 4. 0. 0,]dodeca
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