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SPDV is a cleavable ADC linker used for diagnosis and treatment of cancer or B cell proliferative diseas
Formula: C29H44F3N3O6
Formula: C8H10O2
Temsirolimus treatment for 2 weeks also delays the growth of rapamycin-resistant U251 xenografts by 148%
Pyrimidine-indole hybrid Catalog No.:M34537-C SPDV is a cleavable ADCPyrimidine indole hybrid is a compound that inhibits ciliogenesis and has the activity of antagonizing the Hedgehog signaling pathway by destabilizing microtubules. Pyrimidine indole hybrid exerts its biological effects by inhibiting ciliogenesis and deconstructing the stable form of tubulin. Pyrimidine indole hybrid has shown its unique mechanism of action in in vitro cell experiments and zebrafish embryo models, interfering with microtubule
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