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Chemical Name: 2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1
1 nM in SK-OV-3 cells that calculated from the free fraction in the cell assay
Balamapimod (MKI 833) is a reversible Ras/Raf/MEK inhibitor with potential anti-tumor activity
InChi: InChI=1S/C15H9NO3/c17-15(10-9-12-5-2-1-3-6-12)13-7-4-8-14(11-13)16(18)19/h1-8
N-Oxalylglycine taminyl Cyclase Inhibitor 2 Chemical Name: 2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1The jumonji domain containing protein 2 (JMJD2) subfamily of histone demethylases have been shown to catalyze demethylation of the methylated forms of histone 3 lysine 9 (H3K9) and H3K36 in vitro and in cells. Because histone demethylases are implicated in certain diseases, including cancer, selective inhibitors are candidate anticancer agents as well as potential tools for elucidating the biological functions of JMJDs. 2 N Oxalylglycine, the amide