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1354825-58-3
Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed Inhibitor
Epub 2012 May 5
2013 May 21
SB-743921 HCl Catalog No.:M7949-2 1354825-58-3SB 743921 is a synthetic small molecule with potential antineoplastic properties. SB 743921 selectively inhibits kinesin spindle protein (KSP), an important protein involved in the early stages of mitosis that is expressed in proliferating cells. Inhibition of KSP results in inhibition of mitotic spindle assembly and interrupts cell division, thereby causing cell cycle arrest and induction of apoptosis. Product information CAS Number: 940929 33 9
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